We were lucky enough to have a tour guide (my mom's friend) who actually works with Dale Chihuly take us through the museum. She told us so many neat things. It's so much better than stopping and reading the panels.
This museum is a must-see if you go to Seattle. The wall of Pendelton blankets (he has collected over 800) and the indian portraits were my favorite I think. I loved the garden too. Make sure to go to the collections cafe (pocket knives, bottle openers, accordions, radios and more) . Dale Chihuly gets it.